Are you seeing Object Manager (OM) waits? Did a health check indicate omSize 1024 = 1024 (the default)?

The Object Manager cache should be at least as large as the sum of the number of tables, indexes, and LOBs in the database.

Determine what the -omsize should be by running:

select count(*) from _storageobject.

If that is inconvenient, open the Configuration dashboard in the ProTop Portal and up the numbers in the red boxes below (bottom center of the Configuration dashboard page):

If the total plus 10% is lower than 1024, it is unnecessary to change it.  If it is higher (as it is here), set -omsize to your total plus 10% in your database startup parameter file and restart the database.